Ukusetshenziswa kwemishini yokunyathelisa ye-flexo yohlobo lwe-stack sekuye kwathandwa kakhulu embonini yokunyathelisa ngenxa yamakhono ayo avelele. Le mishini iyakwazi ukushintshashintsha futhi ingaphatha izinhlobo eziningi ze-substrate njengephepha, ipulasitiki, nefilimu. Yenzelwe ukuletha imiphumela yokunyathelisa esezingeni eliphezulu, inikeza ukunemba kokubhalisa okumangalisayo kanye nesivinini sokunyathelisa esisheshayo.

Enye yezinzuzo ezibalulekile zemishini yokunyathelisa ye-flexo yohlobo lwe-stack yikhono layo lokukhiqiza kabusha ihluzo eziyinkimbinkimbi nezinemininingwane ngokunemba okuphezulu. Ikhwalithi yokukhishwa kokunyathelisa ihle kakhulu ngenxa yokusebenzisa ubuchwepheshe obuthuthukisiwe njenge-anilox rolls kanye nama-doctor blades, okuvumela ukudluliselwa kwe-inki ku-substrate ukuze kulawulwe ngokunembe kakhudlwana. Lokhu kuphumela ekuncipheni kwamaphutha okunyathelisa kanye nekhwalithi yomkhiqizo ethuthukisiwe.

Enye inzuzo enkulu yemishini yokunyathelisa ye-flexo yohlobo lwe-stack ukuthi iyakwazi ukuguquguquka. Le mishini inganyathelisa ezindaweni ezahlukene ezinobukhulu obuhlukahlukene, okwenza ifaneleke kakhulu ekunyatheliseni izinhlobo ezahlukene zezinto zokupakisha, amalebula, nezinye izinto. Ngaphezu kwalokho, ukulula kokusebenza kwayo kanye nezikhathi zokusetha okusheshayo kuqinisekisa ukuthi imisebenzi yokunyathelisa ingaqedwa ngokushesha nangendlela efanele.

Ngaphezu kwalokho, imishini yokunyathelisa ye-flexo yohlobo lwe-stack yaziwa ngokuqina kwayo kanye nokuphila isikhathi eside, okwenza kube ukutshalwa kwezimali okuhlakaniphile ezinkampanini ezifuna ukuthuthukisa amakhono azo okunyathelisa. Ngokunakekelwa okuncane kanye nokunakekelwa okuvamile, le mishini ingahlala iminyaka.